Czech anticancer agent works on type 2 diabetes

A team of scientists and physicians from the Institute of Biotechnology of the CAS at the BIOCEV centre and the Institute of Clinical and Experimental Medicine in Prague has demonstrated a positive effect of MitoTam on type 2 diabetes. The research was published today in the prestigious journal Nature Communications.

Type 2 diabetes (D2T) was induced in mouse models by a six-month high-fat diet. "After treatment with MitoTam, body weight dropped almost to the level of mice on the control diet. There was also a reduction in blood glucose and insulin production, indicating suppression of insulin resistance," says Prof. Jiří Neužil, Head of the Laboratory of Molecular Therapy (Institute of Biotechnology of the Czech Academy of Sciences at the BIOCEV Centre). "The substance has also shown an extraordinary effect on the liver, which loses its function during diabetes due to fat deposition and undergoes gradual cirrhosis," adds Prof. Neužil.

Read more here.

Read also

• Scientists discover compound that “should not exist”
• Horizontal mitochondrial transfer is a key process in tumor biology
• Scientists on track of finding a treatment for autoimmune hair loss
• LASER-PRO: Linking Science and Industry to Shape Europe’s High-Tech Future
• Martian mud flows: a little salt makes a big difference
• Violent dance of massive gas giant planets
• Scientists discover new species of rare fungi thanks to arsenic analysis
• MICAL1 plays a key role in cellular dynamics by controlling the cytoskeleton
• Groundbreaking study maps brain’s recovery process after stroke
• IOCB Prague expands overseas, opens a new branch in Boston